Follistatin-related protein 3 (Protein name
), FSTL3_RAT from NCBI database.
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General Annotation
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Antigen Annotation
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3D
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Predicted Eptitope
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Vaild Sequence
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Gene name:
Fstl3(Flrg);
Protein name:
Follistatin-related protein 3;
Alternative:
Follistatin-related gene protein;Follistatin-like protein 3;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Interacts with INHBA and INHBB. Interacts with FN1. Interacts with ADAM12. Interacts with MLLT10; the interaction enhances MLLT10 in vitro transcriptional activity and self-association. Interacts with MSTN.
Function:
The secreted form is a binding and antagonizing protein for members of the TGF-beta family, such us activin, BMP2 and MSTN. Inhibits activin A-, activin B-, BMP2- and MSDT-induced cellular signaling; more effective on activin A than on activin B. Involved in bone formation; inhibits osteoclast differentiation. Involved in hematopoiesis; involved in differentiation of hemopoietic progenitor cells, increases hematopoietic cell adhesion to fibronectin and seems to contribute to the adhesion of hematopoietic precursor cells to the bone marrow stroma. The nuclear form is probably involved in transcriptional regulation via interaction with MLLT10.
Monoclonal Antibody for Rat Follistatin-related protein 3
Monoclonal Antibody for Rat Follistatin-related protein 3
Monoclonal Antibody for Rat Follistatin-related protein 3
Monoclonal Antibody for Rat Follistatin-related protein 3
Protein for Rat Follistatin-related protein 3
Protein for Rat Follistatin-related protein 3
Protein for Rat Follistatin-related protein 3
Protein for Rat Follistatin-related protein 3
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Rat follistatin-related protein FLRG (rat PCTF35, PC12 cell derived trophic factor 35)." Uchiyama Y.
,
Ohsawa Y.
,
Kametaka S.
Submitted (1998-12) to the EMBL/GenBank/DDBJ databases
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Cited for: NUCLEOTIDE SEQUENCE [MRNA]